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Stosuje sie go raz na tydzien w dawce do 1000 mg, hur injicera winstrol. Further, MuRF-1 animals showed relative sparing of fiber size and tension following glucocorticoid myopathy, which was attributed to the preservation of the rate of protein synthesis 36. MuRF-1 has been shown to mainly regulate myofibrillar proteins such as actin, myosin heavy chain, and myosin light chains 1; while atrogin-1 functions as a ligase for several regulatory proteins such as MyoD and eIF3f 37 39. Clearly, suppression of ORX-induced elevations in MuRF-1 and atrogin-1 at least partially mediates the ability of androgens to preserve muscle mass; although, this may not explain the androgen-induced myotrophic actions we observed because MuRF-1 and atrogin-1 were only reduced to the level of intact SHAMs, while LABC muscle mass was increased 40 above SHAMs; suggesting that both anti-catabolic and anabolic processes are involved in androgen-induced muscle growth, . The Akt mTOR signaling pathway is an acknowledged regulator of skeletal muscle mass..

 

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